PKM2 promotes metastasis by recruiting myeloid-derived suppressor cells and indicates poor prognosis for hepatocellular carcinoma

Pyruvate kinase M2 (PKM2) is a member of the pyruvate kinase family. Recent work has defined the “non-metabolic” functions of PKM2. However, the role of PKM2 in HCC remains unclear. To investigate the role of PKM2 in tumor growth, invasion and the prognosis of hepatocellular carcinoma (HCC), PKM2 ex...

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Vydáno v:Oncotarget
Hlavní autoři: Liu, Wei-Ren, Tian, Meng-Xin, Yang, Liu-Xiao, Lin, Yu-Li, Jin, Lei, Ding, Zhen-Bin, Shen, Ying-Hao, Peng, Yuan-Fei, Gao, Dong-Mei, Zhou, Jian, Qiu, Shuang-Jian, Dai, Zhi, He, Rui, Fan, Jia, Shi, Ying-Hong
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359260/
https://ncbi.nlm.nih.gov/pubmed/25514599
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