Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells

Increased glucose metabolism is now recognized as an emerging hallmark of cancer. Recent studies have shown that glucose metabolism is even more active in cancer stem cells (CSCs), a rare population of cancer cells with the capacity to self-renew and initiate tumors, and that CSCs are dependent on g...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Shibuya, Keita, Okada, Masashi, Suzuki, Shuhei, Seino, Manabu, Seino, Shizuka, Takeda, Hiroyuki, Kitanaka, Chifumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359246/
https://ncbi.nlm.nih.gov/pubmed/25528771
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