Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase

Leishmania protozoan parasites (Trypanosomatidae family) are the causative agents of cutaneous, mucocutaneous and visceral leishmaniasis worldwide. While these diseases are associated with significant morbidity and mortality, there are few adequate treatments available. Sterol 14alpha-demethylase (C...

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Detalles Bibliográficos
Publicado en:PLoS Negl Trop Dis
Autores principales: McCall, Laura-Isobel, El Aroussi, Amale, Choi, Jun Yong, Vieira, Debora F., De Muylder, Geraldine, Johnston, Jonathan B., Chen, Steven, Kellar, Danielle, Siqueira-Neto, Jair L., Roush, William R., Podust, Larissa M., McKerrow, James H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359151/
https://ncbi.nlm.nih.gov/pubmed/25768284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003588
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