EFFECT OF A PLURONIC® P123 FORMULATION ON THE NITRIC OXIDE-GENERATING DRUG JS-K

PURPOSE: O(2)-(2,4-dinitrophenyl)1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] or JS-K is a nitric oxide-producing prodrug of the arylated diazeniumdiolate class with promising anti-tumor activity. JS-K has challenging solubility and stability properties. We aimed to characterize and...

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Bibliographic Details
Published in:Pharm Res
Main Authors: Kaur, Imit, Kosak, Ken M., Terrazas, Moises, Herron, James N., Kern, Steven E., Boucher, Kenneth M., Shami, Paul J.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359075/
https://ncbi.nlm.nih.gov/pubmed/25330743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1542-9
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