CDK6 Levels Regulate Quiescence Exit in Human Hematopoietic Stem Cells

Regulated blood production is achieved through the hierarchical organization of dormant hematopoietic stem cell (HSC) subsets that differ in self-renewal potential and division frequency, with long-term (LT)-HSCs dividing the least. The molecular mechanisms underlying this variability in HSC divisio...

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Bibliographic Details
Published in:Cell Stem Cell
Main Authors: Laurenti, Elisa, Frelin, Catherine, Xie, Stephanie, Ferrari, Robin, Dunant, Cyrille F., Zandi, Sasan, Neumann, Andrea, Plumb, Ian, Doulatov, Sergei, Chen, Jing, April, Craig, Fan, Jian-Bing, Iscove, Norman, Dick, John E.
Format: Artigo
Language:Inglês
Published: Cell Press 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359055/
https://ncbi.nlm.nih.gov/pubmed/25704240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.01.017
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