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Design, Synthesis and Biological Evaluation of Theranostic Vitamin-Linker-Taxoid Conjugates
Novel tumor-targeting theranostic conjugates 1 and 2, bearing either a fluorine-labeled prosthetic as a potential (18)F-PET radiotracer (1) or a fluorescence-probe (2) for internalization studies in vitro, were designed and synthesized. We confirmed efficient internalization of 2 in biotin-receptor...
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| 出版年: | J Med Chem |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4359053/ https://ncbi.nlm.nih.gov/pubmed/25654690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm5019115 |
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