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The deubiquitinating enzyme USP24 is a regulator of the UV damage response
Regulation of p53 by ubiquitination and deubiquitination is important for its functions. In this study, we demonstrate that USP24 deubiquitinates p53 in human cells. Functional USP24 is required for p53 stabilization and p53 destabilization in USP24 depleted cells can be corrected by the forced expr...
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| Опубликовано в: : | Cell Rep |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4359050/ https://ncbi.nlm.nih.gov/pubmed/25578727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.12.024 |
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