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MAPping the Ndc80 loop in cancer: A possible link between Ndc80/Hec1 overproduction and cancer formation

Mis-regulation (e.g. overproduction) of the human Ndc80/Hec1 outer kinetochore protein has been associated with aneuploidy and tumourigenesis, but the genetic basis and underlying mechanisms of this phenomenon remain poorly understood. Recent studies have identified the ubiquitous Ndc80 internal loo...

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Bibliografski detalji
Izdano u:Bioessays
Glavni autori: Tang, Ngang Heok, Toda, Takashi
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359004/
https://ncbi.nlm.nih.gov/pubmed/25557589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201400175
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