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MAPping the Ndc80 loop in cancer: A possible link between Ndc80/Hec1 overproduction and cancer formation

Mis-regulation (e.g. overproduction) of the human Ndc80/Hec1 outer kinetochore protein has been associated with aneuploidy and tumourigenesis, but the genetic basis and underlying mechanisms of this phenomenon remain poorly understood. Recent studies have identified the ubiquitous Ndc80 internal loo...

詳細記述

保存先:
書誌詳細
出版年:Bioessays
主要な著者: Tang, Ngang Heok, Toda, Takashi
フォーマット: Artigo
言語:Inglês
出版事項: BlackWell Publishing Ltd 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359004/
https://ncbi.nlm.nih.gov/pubmed/25557589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201400175
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