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Regulation of Autoimmune Germinal Center Reactions in Lupus-Prone BXD2 Mice by Follicular Helper T Cells

BXD2 mice spontaneously develop autoantibodies and subsequent glomerulonephritis, offering a useful animal model to study autoimmune lupus. Although initial studies showed a critical contribution of IL-17 and Th17 cells in mediating autoimmune B cell responses in BXD2 mice, the role of follicular he...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Kim, Young Uk, Lim, Hoyong, Jung, Ha Eun, Wetsel, Rick A., Chung, Yeonseok
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358919/
https://ncbi.nlm.nih.gov/pubmed/25768299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120294
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