Thymic B Cells Promote Germinal Center-Like Structures and the Expansion of Follicular Helper T Cells in Lupus-Prone Mice

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the activation of autoreactive T and B cells, autoantibody production, and immune complex deposition in various organs. Previous evidence showed abnormal accumulation of B cells in the thymus of lupus-prone mice, but the ro...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hidalgo, Yessia, Núñez, Sarah, Fuenzalida, Maria Jose, Flores-Santibáñez, Felipe, Sáez, Pablo J., Dorner, Jessica, Lennon-Dumenil, Ana-Maria, Martínez, Victor, Zorn, Emmanuel, Rosemblatt, Mario, Sauma, Daniela, Bono, Maria Rosa
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199236/
https://ncbi.nlm.nih.gov/pubmed/32411134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00696
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