Transient knockdown-mediated deficiency in plectin alters hepatocellular motility in association with activated FAK and Rac1-GTPase

BACKGROUND: Plectin is one of the cytolinker proteins that play a crucial role in maintaining the integrity of cellular architecture. It is a component of desmosome complexes connecting cytoskeletal proteins and trans-membrane molecules. In epithelial cells, plectin connects cytokeratins and integri...

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Bibliographic Details
Published in:Cancer Cell Int
Main Authors: Cheng, Chiung-Chi, Lai, Yen-Chang Clark, Lai, Yih-Shyong, Hsu, Yung-Hsiang, Chao, Wei-Ting, Sia, Kee-Chin, Tseng, Yu-Hui, Liu, Yi-Hsiang
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Primary Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358909/
https://ncbi.nlm.nih.gov/pubmed/25774093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-015-0177-1
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