Plectin deficiency in liver cancer cells promotes cell migration and sensitivity to sorafenib treatment

Plectin involved in activation of kinases in cell signaling pathway and plays important role in cell morphology and migration. Plectin knockdown promotes cell migration by activating focal adhesion kinase and Rac1-GTPase activity in liver cells. Sorafenib is a multi-targeting tyrosine kinase inhibit...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Adh Migr
Autori principali: Cheng, Chiung-Chi, Chao, Wei-Ting, Liao, Chen-Chun, Tseng, Yu-Hui, Lai, Yen-Chang Clark, Lai, Yih-Shyong, Hsu, Yung-Hsiang, Liu, Yi-Hsiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810502/
https://ncbi.nlm.nih.gov/pubmed/28276928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2017.1288789
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