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sCLU regulates cisplatin chemosensitivity of lung cancer cells in vivo

BACKGROUND: In a previous analysis using a lung cancer cell line model, we have found that therapies directed against secreted clusterin (sCLU) and its downstream signaling targets pAkt and pERK1/2 may have the potential to enhance the efficacy of cisplatin (DDP)-based chemotherapy in vitro. Here, w...

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Bibliografiske detaljer
Udgivet i:World J Surg Oncol
Main Authors: Ma, Guoliang, Cai, Hengjuan, Gao, Lizhen, Wang, Mei, Wang, Haixia
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358856/
https://ncbi.nlm.nih.gov/pubmed/25884382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12957-015-0501-1
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