Statin myalgia is not associated with reduced muscle strength, mass or protein turnover in older male volunteers, but is allied with a slowing of time to peak power output, insulin resistance and differential muscle mRNA expression

KEY POINTS: Statins cause muscle‐specific side effects, most commonly muscle aches/weakness (myalgia), particularly in older people. Furthermore, evidence has linked statin use to increased risk of type 2 diabetes. However, the mechanisms involved are unknown. This is the first study to measure musc...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Mallinson, Joanne E., Marimuthu, Kanagaraj, Murton, Andrew, Selby, Anna, Smith, Kenneth, Constantin‐Teodosiu, Dumitru, Rennie, Michael J., Greenhaff, Paul L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Muscle
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358682/
https://ncbi.nlm.nih.gov/pubmed/25620655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.285577
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