Pressor responsiveness to angiotensin II in female mice is enhanced with age: role of the angiotensin type 2 receptor

BACKGROUND: The pressor response to angiotensin II (AngII) is attenuated in adult females as compared to males via an angiotensin type 2 receptor (AT(2)R)-dependent pathway. We hypothesized that adult female mice are protected against AngII-induced hypertension via an enhanced AT(2)R-mediated pathwa...

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Vydáno v:Biol Sex Differ
Hlavní autoři: Mirabito, Katrina M, Hilliard, Lucinda M, Head, Geoffrey A, Widdop, Robert E, Denton, Kate M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358320/
https://ncbi.nlm.nih.gov/pubmed/25774285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13293-014-0013-7
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