Cytotoxicity of immunoglobulins from amyotrophic lateral sclerosis patients on a hybrid motoneuron cell line.

Patients with amyotrophic lateral sclerosis possess antibodies (ALS IgGs) that bind to L-type skeletal muscle voltage-gated calcium channels (VGCCs) and inhibit L-type calcium current. To determine whether interaction of ALS IgGs with neuronal VGCCs might influence motoneuron survival, we used a mot...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Smith, R G, Alexianu, M E, Crawford, G, Nyormoi, O, Stefani, E, Appel, S H
Formato: Artigo
Idioma:Inglês
Publicado: 1994
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC43583/
https://ncbi.nlm.nih.gov/pubmed/8159758
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares