Aldo-keto Reductase 1B15 (AKR1B15): A MITOCHONDRIAL HUMAN ALDO-KETO REDUCTASE WITH ACTIVITY TOWARD STEROIDS AND 3-KETO-ACYL-CoA CONJUGATES

Aldo-keto reductases (AKRs) comprise a superfamily of proteins involved in the reduction and oxidation of biogenic and xenobiotic carbonyls. In humans, at least 15 AKR superfamily members have been identified so far. One of these is a newly identified gene locus, AKR1B15, which clusters on chromosom...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Weber, Susanne, Salabei, Joshua K., Möller, Gabriele, Kremmer, Elisabeth, Bhatnagar, Aruni, Adamski, Jerzy, Barski, Oleg A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Enzymology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358287/
https://ncbi.nlm.nih.gov/pubmed/25577493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.610121
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