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MicroRNA-520g Confers Drug Resistance by Regulating p21 Expression in Colorectal Cancer

Development of drug resistance is one of the major causes of colorectal cancer recurrence, yet mechanistic understanding and therapeutic options remain limited. Here, we show that expression of microRNA (miR)-520g is correlated with drug resistance of colon cancer cells. Ectopic expression of miR-52...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zhang, Yang, Geng, Liying, Talmon, Geoffrey, Wang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358260/
https://ncbi.nlm.nih.gov/pubmed/25616665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.620252
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