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Polyamine Metabolism Is Sensitive to Glycolysis Inhibition in Human Neuroblastoma Cells
Polyamines are essential for cell proliferation, and their levels are elevated in many human tumors. The oncogene n-myc is known to potentiate polyamine metabolism. Neuroblastoma, the most frequent extracranial solid tumor in children, harbors the amplification of n-myc oncogene in 25% of the cases,...
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| Publicado en: | J Biol Chem |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4358251/ https://ncbi.nlm.nih.gov/pubmed/25593318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.619197 |
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