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Polyamine Metabolism Is Sensitive to Glycolysis Inhibition in Human Neuroblastoma Cells

Polyamines are essential for cell proliferation, and their levels are elevated in many human tumors. The oncogene n-myc is known to potentiate polyamine metabolism. Neuroblastoma, the most frequent extracranial solid tumor in children, harbors the amplification of n-myc oncogene in 25% of the cases,...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Ruiz-Pérez, M. Victoria, Medina, Miguel Ángel, Urdiales, José Luis, Keinänen, Tuomo A., Sánchez-Jiménez, Francisca
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2015
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358251/
https://ncbi.nlm.nih.gov/pubmed/25593318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.619197
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