The Oncogenic MicroRNA-21 Inhibits the Tumor Suppressive Activity of FBXO11 to Promote Tumorigenesis

The microRNA miR-21 is overexpressed in most human cancers and accumulating evidence indicates that it functions as an oncogene. Since miRNAs suppress the expression of their target genes, we hypothesized that some miR-21 targets may act as tumor suppressors, and thus their expression would be antic...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Biol Chem
मुख्य लेखकों: Yang, Chuan He, Pfeffer, Susan R., Sims, Michelle, Yue, Junming, Wang, Yinan, Linga, Vijay G., Paulus, Elena, Davidoff, Andrew M., Pfeffer, Lawrence M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2015
विषय:
Molecular Bases of Disease
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358246/
https://ncbi.nlm.nih.gov/pubmed/25589783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.632125
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