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SH2B1 and IRSp53 Proteins Promote the Formation of Dendrites and Dendritic Branches

SH2B1 is an adaptor protein known to enhance neurite outgrowth. In this study, we provide evidence suggesting that the SH2B1 level is increased during in vitro culture of hippocampal neurons, and the β isoform (SH2B1β) is the predominant isoform. The fact that formation of filopodia is prerequisite...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Chen, Chien-Jen, Shih, Chien-Hung, Chang, Yu-Jung, Hong, Shao-Jing, Li, Tian-Neng, Wang, Lily Hui-Ching, Chen, Linyi
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358244/
https://ncbi.nlm.nih.gov/pubmed/25586189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.603795
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