High-Throughput Analysis of Gene Essentiality and Sporulation in Clostridium difficile

Clostridium difficile is the most common cause of antibiotic-associated intestinal infections and a significant cause of morbidity and mortality. Infection with C. difficile requires disruption of the intestinal microbiota, most commonly by antibiotic usage. Therapeutic intervention largely relies o...

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Publicado en:mBio
Autores principales: Dembek, Marcin, Barquist, Lars, Boinett, Christine J., Cain, Amy K., Mayho, Matthew, Lawley, Trevor D., Fairweather, Neil F., Fagan, Robert P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358009/
https://ncbi.nlm.nih.gov/pubmed/25714712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02383-14
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