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Distinct DNA-binding properties of the high mobility group domain of murine and human SRY sex-determining factors.

The mammalian sex-determining gene SRY (sex-determining region on Y chromosome) encodes a member of the high mobility group (HMG) family of regulatory proteins. The HMG domain of the SRY protein represents a DNA binding motif that displays rather unusually weak evolutionary conservation of amino aci...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Giese, K, Pagel, J, Grosschedl, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1994
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43578/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8159753/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.8.3368
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