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Dissecting the role of the ϕ29 terminal protein DNA binding residues in viral DNA replication

Phage ϕ29 DNA replication takes place by a protein-priming mechanism in which the viral DNA polymerase catalyses the covalent linkage of the initiating nucleotide to a specific serine residue of the terminal protein (TP). The N-terminal domain of the ϕ29 TP has been shown to bind to the host DNA in...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Holguera, Isabel, Muñoz-Espín, Daniel, Salas, Margarita
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357725/
https://ncbi.nlm.nih.gov/pubmed/25722367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv127
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