A novel endonuclease that may be responsible for damaged DNA base repair in Pyrococcus furiosus

DNA is constantly damaged by endogenous and environmental influences. Deaminated adenine (hypoxanthine) tends to pair with cytosine and leads to the A:T→G:C transition mutation during DNA replication. Endonuclease V (EndoV) hydrolyzes the second phosphodiester bond 3′ from deoxyinosine in the DNA st...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Shiraishi, Miyako, Ishino, Sonoko, Yamagami, Takeshi, Egashira, Yuriko, Kiyonari, Shinichi, Ishino, Yoshizumi
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Nucleic Acid Enzymes
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357722/
https://ncbi.nlm.nih.gov/pubmed/25694513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv121
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