A novel endonuclease that may be responsible for damaged DNA base repair in Pyrococcus furiosus

DNA is constantly damaged by endogenous and environmental influences. Deaminated adenine (hypoxanthine) tends to pair with cytosine and leads to the A:T→G:C transition mutation during DNA replication. Endonuclease V (EndoV) hydrolyzes the second phosphodiester bond 3′ from deoxyinosine in the DNA st...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Shiraishi, Miyako, Ishino, Sonoko, Yamagami, Takeshi, Egashira, Yuriko, Kiyonari, Shinichi, Ishino, Yoshizumi
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
Nucleic Acid Enzymes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357722/
https://ncbi.nlm.nih.gov/pubmed/25694513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv121
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