Single-molecule kinetics and footprinting of DNA bis-intercalation: the paradigmatic case of Thiocoraline

DNA bis-intercalators are widely used in molecular biology with applications ranging from DNA imaging to anticancer pharmacology. Two fundamental aspects of these ligands are the lifetime of the bis-intercalated complexes and their sequence selectivity. Here, we perform single-molecule optical tweez...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Camunas-Soler, Joan, Manosas, Maria, Frutos, Silvia, Tulla-Puche, Judit, Albericio, Fernando, Ritort, Felix
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357703/
https://ncbi.nlm.nih.gov/pubmed/25690887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv087
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky