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Single-molecule kinetics and footprinting of DNA bis-intercalation: the paradigmatic case of Thiocoraline
DNA bis-intercalators are widely used in molecular biology with applications ranging from DNA imaging to anticancer pharmacology. Two fundamental aspects of these ligands are the lifetime of the bis-intercalated complexes and their sequence selectivity. Here, we perform single-molecule optical tweez...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4357703/ https://ncbi.nlm.nih.gov/pubmed/25690887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv087 |
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