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SwiftLib: rapid degenerate-codon-library optimization through dynamic programming

Degenerate codon (DC) libraries efficiently address the experimental library-size limitations of directed evolution by focusing diversity toward the positions and toward the amino acids (AAs) that are most likely to generate hits; however, manually constructing DC libraries is challenging, error pro...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Jacobs, Timothy M., Yumerefendi, Hayretin, Kuhlman, Brian, Leaver-Fay, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357694/
https://ncbi.nlm.nih.gov/pubmed/25539925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1323
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