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Rab5-family guanine nucleotide exchange factors bind retromer and promote its recruitment to endosomes

The retromer complex facilitates the sorting of integral membrane proteins from the endosome to the late Golgi. In mammalian cells, the efficient recruitment of retromer to endosomes requires the lipid phosphatidylinositol 3-phosphate (PI3P) as well as Rab5 and Rab7 GTPases. However, in yeast, the r...

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Bibliografski detalji
Izdano u:Mol Biol Cell
Glavni autori: Bean, Bjorn D. M., Davey, Michael, Snider, Jamie, Jessulat, Matthew, Deineko, Viktor, Tinney, Matthew, Stagljar, Igor, Babu, Mohan, Conibear, Elizabeth
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2015
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357511/
https://ncbi.nlm.nih.gov/pubmed/25609093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-08-1281
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