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Rab5-family guanine nucleotide exchange factors bind retromer and promote its recruitment to endosomes
The retromer complex facilitates the sorting of integral membrane proteins from the endosome to the late Golgi. In mammalian cells, the efficient recruitment of retromer to endosomes requires the lipid phosphatidylinositol 3-phosphate (PI3P) as well as Rab5 and Rab7 GTPases. However, in yeast, the r...
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| Udgivet i: | Mol Biol Cell |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4357511/ https://ncbi.nlm.nih.gov/pubmed/25609093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-08-1281 |
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