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Rab5-family guanine nucleotide exchange factors bind retromer and promote its recruitment to endosomes

The retromer complex facilitates the sorting of integral membrane proteins from the endosome to the late Golgi. In mammalian cells, the efficient recruitment of retromer to endosomes requires the lipid phosphatidylinositol 3-phosphate (PI3P) as well as Rab5 and Rab7 GTPases. However, in yeast, the r...

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Publicat a:Mol Biol Cell
Autors principals: Bean, Bjorn D. M., Davey, Michael, Snider, Jamie, Jessulat, Matthew, Deineko, Viktor, Tinney, Matthew, Stagljar, Igor, Babu, Mohan, Conibear, Elizabeth
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357511/
https://ncbi.nlm.nih.gov/pubmed/25609093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-08-1281
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