Fibrinogen-Like Protein 2/Fibroleukin Induces Long-Term Allograft Survival in a Rat Model through Regulatory B Cells

We previously described that in a rat model of heart transplantation tolerance was dependent on CD8(+)CD45RC(low) Tregs that over-expressed fibrinogen-like protein 2 (FGL2)/fibroleukin. Little is known on the immunoregulatory properties of FGL2. Here we analyzed the transplantation tolerance mechani...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Bézie, Séverine, Picarda, Elodie, Tesson, Laurent, Renaudin, Karine, Durand, Justine, Ménoret, Séverine, Mérieau, Emmanuel, Chiffoleau, Elise, Guillonneau, Carole, Caron, Lise, Anegon, Ignacio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357433/
https://ncbi.nlm.nih.gov/pubmed/25763980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119686
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