Requirement for interleukin-1 to drive brain inflammation reveals tissue-specific mechanisms of innate immunity

The immune system is implicated in a wide range of disorders affecting the brain and is, therefore, an attractive target for therapy. Interleukin-1 (IL-1) is a potent regulator of the innate immune system important for host defense but is also associated with injury and disease in the brain. Here, w...

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Vydáno v:Eur J Immunol
Hlavní autoři: Giles, James A, Greenhalgh, Andrew D, Davies, Claire L, Denes, Adam, Shaw, Tovah, Coutts, Graham, Rothwell, Nancy J, McColl, Barry W, Allan, Stuart M
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2015
Témata:
Innate Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357393/
https://ncbi.nlm.nih.gov/pubmed/25367678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201444748
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