Renal and Metabolic Toxicities Following Initiation of HIV-1 Treatment Regimen in a Diverse, Multinational Setting: A Focused Safety Analysis of ACTG PEARLS (A5175)

BACKGROUND: Convenient dosing, potency, and low toxicity support use of tenofovir disoproxil fumarate (TDF) as preferred nucleotide reverse transcriptase inhibitor (NRTI) for HIV-1 treatment. However, renal and metabolic safety of TDF compared to other NRTIs has not been well described in resource-l...

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Publicado en:HIV Clin Trials
Autores principales: Romo, F. Touzard, Smeaton, L.M., Campbell, T.B., Riviere, C., Mngqibisa, R., Nyirenda, M., Supparatpinyo, K., Kumarasamy, N., Hakim, J.G., Flanigan, T.P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357257/
https://ncbi.nlm.nih.gov/pubmed/25433664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1310/hct1506-246
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