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Pretreatment HIV Drug Resistance and HIV-1 Subtype C Are Independently Associated With Virologic Failure: Results From the Multinational PEARLS (ACTG A5175) Clinical Trial

Background. Evaluation of pretreatment HIV genotyping is needed globally to guide treatment programs. We examined the association of pretreatment (baseline) drug resistance and subtype with virologic failure in a multinational, randomized clinical trial that evaluated 3 antiretroviral treatment (ART...

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Pubblicato in:Clin Infect Dis
Autori principali: Kantor, Rami, Smeaton, Laura, Vardhanabhuti, Saran, Hudelson, Sarah E., Wallis, Carol L., Tripathy, Srikanth, Morgado, Mariza G., Saravanan, Shanmugham, Balakrishnan, Pachamuthu, Reitsma, Marissa, Hart, Stephen, Mellors, John W., Halvas, Elias, Grinsztejn, Beatriz, Hosseinipour, Mina C., Kumwenda, Johnstone, La Rosa, Alberto, Lalloo, Umesh G., Lama, Javier R., Rassool, Mohammed, Santos, Breno R., Supparatpinyo, Khuanchai, Hakim, James, Flanigan, Timothy, Kumarasamy, Nagalingeswaran, Campbell, Thomas B., Eshleman, Susan H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425827/
https://ncbi.nlm.nih.gov/pubmed/25681380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/civ102
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