PGE(2)-Induced IDO1 Inhibits the Capacity of Fully Mature DCs to Elicit an In Vitro Antileukemic Immune Response

In the last years, dendritic cells (DC) have been evaluated for antitumor vaccination. Although DC-based vaccines have raised great expectations, their clinical translation has been largely disappointing. For these results, several explanations have been proposed. In particular, the concomitant expr...

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Bibliografiske detaljer
Udgivet i:J Immunol Res
Main Authors: Trabanelli, Sara, Lecciso, Mariangela, Salvestrini, Valentina, Cavo, Michele, Očadlíková, Darina, Lemoli, Roberto M., Curti, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357138/
https://ncbi.nlm.nih.gov/pubmed/25815345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/253191
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