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Identification of AMP-activated protein kinase targets by a consensus sequence search of the proteome

BACKGROUND: AMP-activated protein kinase (AMPK) is a heterotrimeric serine/threonine protein kinase that is activated by cellular perturbations associated with ATP depletion or stress. While AMPK modulates the activity of a variety of targets containing a specific phosphorylation consensus sequence,...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Marin, Traci L, Gongol, Brendan, Martin, Marcy, King, Stephanie J, Smith, Lemar, Johnson, David A, Subramaniam, Shankar, Chien, Shu, Shyy, John Y-J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357066/
https://ncbi.nlm.nih.gov/pubmed/25890336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0156-0
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