Autophagy Regulates Colistin-Induced Apoptosis in PC-12 Cells

Colistin is a cyclic cationic polypeptide antibiotic with activity against multidrug-resistant Gram-negative bacteria. Our recent study demonstrated that colistin induces apoptosis in primary chick cortex neurons and PC-12 cells. Although apoptosis and autophagy have different impacts on cell fate,...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Zhang, Ling, Zhao, Yonghao, Ding, Wenjian, Jiang, Guozheng, Lu, Ziyin, Li, Li, Wang, Jinli, Li, Jian, Li, Jichang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
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Mechanisms of Action: Physiological Effects
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356802/
https://ncbi.nlm.nih.gov/pubmed/25645826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04092-14
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