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Antipseudomonal Agents Exhibit Differential Pharmacodynamic Interactions with Human Polymorphonuclear Leukocytes against Established Biofilms of Pseudomonas aeruginosa

Pseudomonas aeruginosa is the most common pathogen infecting the lower respiratory tract of cystic fibrosis (CF) patients, where it forms tracheobronchial biofilms. Pseudomonas biofilms are refractory to antibacterials and to phagocytic cells with innate immunity, leading to refractory infection. Li...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Chatzimoschou, Athanasios, Simitsopoulou, Maria, Antachopoulos, Charalampos, Walsh, Thomas J., Roilides, Emmanuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356800/
https://ncbi.nlm.nih.gov/pubmed/25645829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04934-14
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