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Antipseudomonal Agents Exhibit Differential Pharmacodynamic Interactions with Human Polymorphonuclear Leukocytes against Established Biofilms of Pseudomonas aeruginosa

Pseudomonas aeruginosa is the most common pathogen infecting the lower respiratory tract of cystic fibrosis (CF) patients, where it forms tracheobronchial biofilms. Pseudomonas biofilms are refractory to antibacterials and to phagocytic cells with innate immunity, leading to refractory infection. Li...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Chatzimoschou, Athanasios, Simitsopoulou, Maria, Antachopoulos, Charalampos, Walsh, Thomas J., Roilides, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356800/
https://ncbi.nlm.nih.gov/pubmed/25645829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04934-14
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