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Major Pathways of Polymyxin-Induced Apoptosis in Rat Kidney Proximal Tubular Cells

Identifying the pathways involved in the apoptotic cell death that is associated with polymyxin-induced nephrotoxicity is crucial for the development of strategies to ameliorate this dose-limiting side effect and for the development of novel safer polymyxins. The primary aim of this study was to ide...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Azad, Mohammad A. K., Akter, Jesmin, Rogers, Kelly L., Nation, Roger L., Velkov, Tony, Li, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356794/
https://ncbi.nlm.nih.gov/pubmed/25624331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04869-14
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