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Eravacycline (TP-434) Is Active In Vitro against Biofilms Formed by Uropathogenic Escherichia coli

Eravacycline (formerly TP-434) was evaluated in vitro against pre-established biofilms formed by a uropathogenic Escherichia coli strain. Biofilms were eradicated by 0.5 μg/ml eravacycline, which was within 2-fold of the MIC for planktonic cells. In contrast, colistin and meropenem disrupted biofilm...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Grossman, Trudy H., O'Brien, William, Kerstein, Kathryn O., Sutcliffe, Joyce A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356792/
https://ncbi.nlm.nih.gov/pubmed/25624334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04967-14
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