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Search for Novel Candidate Mutations for Metronidazole Resistance in Helicobacter pylori Using Next-Generation Sequencing

Metronidazole resistance is a key factor associated with Helicobacter pylori treatment failure. Although this resistance is mainly associated with mutations in the rdxA and frxA genes, the question of whether metronidazole resistance is caused by the inactivation of frxA alone is still debated. Furt...

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Библиографические подробности
Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Binh, Tran Thanh, Suzuki, Rumiko, Trang, Tran Thi Huyen, Kwon, Dong Hyeon, Yamaoka, Yoshio
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356779/
https://ncbi.nlm.nih.gov/pubmed/25645832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04852-14
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