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Search for Novel Candidate Mutations for Metronidazole Resistance in Helicobacter pylori Using Next-Generation Sequencing

Metronidazole resistance is a key factor associated with Helicobacter pylori treatment failure. Although this resistance is mainly associated with mutations in the rdxA and frxA genes, the question of whether metronidazole resistance is caused by the inactivation of frxA alone is still debated. Furt...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Binh, Tran Thanh, Suzuki, Rumiko, Trang, Tran Thi Huyen, Kwon, Dong Hyeon, Yamaoka, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356779/
https://ncbi.nlm.nih.gov/pubmed/25645832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04852-14
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