Discovery of novel mutations for clarithromycin resistance in Helicobacter pylori by using next-generation sequencing

OBJECTIVES: Resistance to clarithromycin is the most important factor causing failure of Helicobacter pylori eradication. Although clarithromycin resistance is mainly associated with three point mutations in the 23S rRNA genes, it is unclear whether other mutations are associated with this resistanc...

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Detalhes bibliográficos
Main Authors: Binh, Tran Thanh, Shiota, Seiji, Suzuki, Rumiko, Matsuda, Miyuki, Trang, Tran Thi Huyen, Kwon, Dong Hyeon, Iwatani, Shun, Yamaoka, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054984/
https://ncbi.nlm.nih.gov/pubmed/24648504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku050
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