Biochemical Characterization of Recombinant Enterovirus 71 3C Protease with Fluorogenic Model Peptide Substrates and Development of a Biochemical Assay

Enterovirus 71 (EV71), a primary pathogen of hand, foot, and mouth disease (HFMD), affects primarily infants and children. Currently, there are no effective drugs against HFMD. EV71 3C protease performs multiple tasks in the viral replication, which makes it an ideal antiviral target. We synthesized...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Shang, Luqing, Zhang, Shumei, Yang, Xi, Sun, Jixue, Li, Linfeng, Cui, Zhengjie, He, Qiuhong, Guo, Yu, Sun, Yuna, Yin, Zheng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2015
Konular:
Antiviral Agents
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356770/
https://ncbi.nlm.nih.gov/pubmed/25421478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04698-14
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