Experimental Resistance to Drug Combinations in Leishmania donovani: Metabolic and Phenotypic Adaptations

Together with vector control, chemotherapy is an essential tool for the control of visceral leishmaniasis (VL), but its efficacy is jeopardized by growing resistance and treatment failure against first-line drugs. To delay the emergence of resistance, the use of drug combinations of existing antilei...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Berg, Maya, García-Hernández, Raquel, Cuypers, Bart, Vanaerschot, Manu, Manzano, José I., Poveda, José A., Ferragut, José A., Castanys, Santiago, Dujardin, Jean-Claude, Gamarro, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356759/
https://ncbi.nlm.nih.gov/pubmed/25645828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04231-14
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