Two Mechanisms of Killing of Pseudomonas aeruginosa by Tobramycin Assessed at Multiple Inocula via Mechanism-Based Modeling

Bacterial resistance is among the most serious threats to human health globally, and many bacterial isolates have emerged that are resistant to all antibiotics in monotherapy. Aminoglycosides are often used in combination therapies against severe infections by multidrug-resistant bacteria. However,...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Bulitta, Jürgen B., Ly, Neang S., Landersdorfer, Cornelia B., Wanigaratne, Nicholin A., Velkov, Tony, Yadav, Rajbharan, Oliver, Antonio, Martin, Lisandra, Shin, Beom Soo, Forrest, Alan, Tsuji, Brian T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356757/
https://ncbi.nlm.nih.gov/pubmed/25645838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04099-14
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