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Portion-mixing peptide libraries of quenched fluorogenic substrates for complete subsite mapping of endoprotease specificity.

A solid-phase assay for the complete subsite mapping of the active site of endoproteases has been developed. A library of resin-bound protease substrates was synthesized both on kieselguhr-supported polyamide resin and on a polyethylene glycol-poly-(N,N-dimethylacrylamide) copolymer type of resin th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Meldal, M, Svendsen, I, Breddam, K, Auzanneau, F I
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC43567/
https://ncbi.nlm.nih.gov/pubmed/8159745
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