Effects of targeted phosphorylation site mutations in the DNA-PKcs phosphorylation domain on low and high LET radiation sensitivity

The present study investigated the effect of targeted mutations in the DNA-dependent protein kinase catalytic subunit and phosphorylation domains on the survival of cells in response to different qualities of ionizing radiation. Mutated Chinese hamster ovary V3 cells were exposed to 500 MeV/nucleon...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: CARTWRIGHT, IAN M., BELL, JUSTIN J., MAEDA, JUNKO, GENET, MATTHEW D., ROMERO, ASHLEY, FUJII, YOSHIHIRO, FUJIMORI, AKIRA, KITAMUTA, HISASHI, KAMADA, TADASHI, CHEN, DAVID J., KATO, TAKAMITSU A.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356358/
https://ncbi.nlm.nih.gov/pubmed/25789011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.2974
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